Reproduction Final Part 1 (Pozor) Flashcards
Define: Aneuploidy
Increase or decrease in normal chromosome number (usually only by one chromosome), leading to trisomy or monosomy.
Define: Chimera
An individual having embryonic tissue from two different individuals.
Define: Diploid
Number of chromosomes in somatic cells (2N).
Define: Gonadal dysgenesis
Gonads fail to differentiate and remain in embryonic form, termed “streak” gonads.
Define: Haploid
Number of chromosomes in a gamete (N).
Define: Hermaphrodite
An individual having both testicular and ovarian tissue.
Define: Intersex
Any situation in which there is ambiguity in the structure of external genitalia, internal genitalia, or gonads.
Define: Monosomy
Loss of one chromosome from a homologous pair.
Define: Mosaic
Individual having cell lines with two different genotypes.
Define: Pseudohermaphroditic
An individual having the chromosomes and gonads of one sex, with the opposite phenotype.
Define: Trisomy
Extra chromosome added to a homologous pair.
Define: Chromosomal (genotypic) sex
Determined at fertilization in mammals by the type of sex chromosome contributed by the sperm (X or Y).
Define: Gonadal sex
Determined by the presence or absence of the Sry gene of the Y chromosome, and other genes.
What is the Sry gene?
Sex-determining region of the Y-chromosome
Define: Phenotypic sex
Determined by substances produces in the testis that cause regression of the female tract and maintenance of the male tract, or, in the absence of a testis, maintenance of the female tract and regression of the male tract. These substances also regulate the development of external genitalia, secondary sex characteristics, development of the brain, and other characteristics related to phenotype.
T/F: The early stages of sexual differentiation are exactly the same for males and females.
TRUE
What is the precursor of the gonad in either sex?
Genital ridge
What’s another name for the Wolffian ducts? For the Mullerian ducts?
Wolffian –> Mesonephros
Mullerian –> Paramesonephros
T/F: Female is the default process for the gonads.
FALSE
During the development of a male fetus, what type of cells are especially important due to their role as a testosterone producer?
Fetal Leydig cells