Rubella

Question 1

Does Rubella target DNA or RNA?

Answer 1

RNA

Question 2

What percentage of Rubella patients are asymptomatic?

Answer 2

25-50%

Question 3

When are Rubella patients most communicable? Does it have a long or short incubation period?

Answer 3

Few days before and 5-7 days after onset of rash

Long-ranges from 14-23 days usually 16-18

Question 4

When does Rubella usually present? (time of year)

Answer 4

Late winter/early spring

Question 5

Name the clinical manifestations of Rubella

Answer 5

• Usually mild dz
• Generalized rash that spreads from face caudally to trunk and extremities within 24 hours
• General lymphadenopathy (suboccipital, postauricular and cervical)
• Low grade fever

Question 6

What are the clinical manifestations of Congenital Rubella Syndrome?

Answer 6

1. Ophthalmologic- cataracts, retinopathy, glaucoma
2. Cardiac- Heart defect, peripheral pulmonary artery stenosis
3. Auditory**- most common manifestation causing deafness
4. Neurologic- behavior disorder, meningoencephalitis, mental retardation

Question 7

Congenital defects are how much more likely if infection occurs in the first month of pregnancy?

Answer 7

50%

Question 8

How do we test for rubella?

Answer 8

Throat swabs, blood, urine, CSF, antibody titer

Question 9

How do we treat Rubella?

Answer 9

Supportive care, children should be excluded for school for 7 days after rash onset

Question 10

Children with congenital rubella should be considered contagious until they are one year old unless______ and _______ are repeatedly negative for rubella virus

Answer 10

nasopharyngeal, urine cultures