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Pharmacology - EYE > Pegaptanib > Flashcards

Pegaptanib Flashcards

1
Q

MOA

A
  • Attached polyethylene glycol to drug molecule
  • Decreases antigenicity
  • Increases molecular size to decrease renal clearance
  • Increases water solubility
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2
Q

Indications

A

Wet AMD

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3
Q

Warning/precautions

A

Pregnancy category B

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4
Q

Adverse reactions

A
  • Endophthalmitis and increased IOP after injection
  • Blepharitis
  • Conjunctivitis
  • Photopsia
  • Bronchitis
  • Diarrhea, dizziness, headache, nausea, UTI
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5
Q

Brand name

A

Macugen

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Pharmacology - EYE (20 decks)

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