Parkinsons

Question 1

General SE of Parkinson meds?

Answer 1

Anticholinergic (like everything else)

+CTRZ (N/V)

Question 2

General MOA of Parkinson meds?

Answer 2

Increase dopamine. PO

Question 3

1 treatment for Parkinsons?

Answer 3

Levadopa

Question 4

What percent of Ldopa reaches the brain?

Answer 4

1%

Question 5

What should you not be taking if taking Ldopa?

Answer 5

MAO inhibitors =HTN

Question 6

What is sometimes added to Ldopa to increase the chances of more Ldopa reaching the brain, rather than being broken down in periphery?

Answer 6

Carbidopa

Question 7

Weird SE of Cardiopa?

Answer 7

Hallucinations

Question 8

2 treatment choice?

Answer 8

Pariodel

Question 9

What type of drug/MOA is Pariodel? Short answer, weird question.

Answer 9

Dopamine agonist

Question 10

Since Pariodel is a dopamine agonist, what is it also helpful to treat?

Answer 10

Prolactin secreting tumors.

…and Neuro malmenant syndrome (not sure why-just is, bonus question: this syndrome may be a SE of what?)

….Haldol (typical antipsychotic)…everythings connected

Question 11

3 treatment option?

Answer 11

Amantadine

Question 12

Why do we already know Amantadine?

Answer 12

Anti viral: Influenza A

Question 13

Do you develop tolerance to Amantadine?

Answer 13

Yes, around 6m

Question 14

4 tx option?

Answer 14

Benztropine

Question 15

What type of drug/MOA is Benztropine. think TROPINEq

Answer 15

Anticholinergic

Question 16

What do you take when you turn into Belle because you have overdosed on Benztropine (yes throw back to homeopathy, sort belladonna but not)

Answer 16

Physostigmine