BioChemistry Flashcards

1
Q

IgM

A

First AB made in response to an antigen

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2
Q

IgG

A

Most common. 2nd response. Can cross placenta

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3
Q

IgA

A

Present in blood, tears, milk

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4
Q

IgD

A

Present on B Lymphocytes

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5
Q

IgE

A

Type 1 hypersensitivity reactions

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6
Q

What is collegen made up of

A

glycine-X-X (commonly lysine and proline)

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7
Q

Where is Type I collagen found in the body

A

bowmans and sclera and bone

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8
Q

Where it type IV found in the body

A

viterous

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9
Q

Competitive enzymes

A

will increase Km bu Vmax the same

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10
Q

non competitive enzymes

A

not affect on Km but will reduce Vmax

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11
Q

Monose

A

Glucose + glucose

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12
Q

Lactose

A

glucose + galactose

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13
Q

Sucrose

A

glucose + fructose

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14
Q

NADPH

A

makes FA, lipids, steroids

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15
Q

NADH/FADH

A

makes ATP

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16
Q

What can Acetyl-CoA make

A

ATP, ketone bodies, malanyl-coA, cholesterol

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17
Q

What is used for gluconeogensis

A

LAG. Lactic, amino acids, glycine

18
Q

Pentose shunt

A

Makes NADPH

19
Q

Gluconeogensis

A

Make new glucose when starving. glucagon.

20
Q

glycogenesis

A

store glucose. insulin

21
Q

Glycogenelysis

A

break down glucose storage. Glucagon.

22
Q

What is cholesterol precursor for

A

mineralocorticoids and glucocorticoids

23
Q

Ketone bodies

A

acetyl acetate, beta-hydroxybutyrate, acetone

24
Q

Omega 3

A

Anti-inflammatory. ALA = EPA + DHA. Alpha linolenic acid, eicospentenoic acid, docosohexaenoic acid.

25
Q

Omega 6

A

pro-inflammatory. aracnidi acid

26
Q

Fat Soluble vitamins

A

DEAK

27
Q

Anti-oxidants

A

ACE + zinc

28
Q

Vitamin B1

A

Thiamine. Decreased with alcoholism.

29
Q

Vitamine B12

A

Cobalamin. Pernicious anemia destroys parietal cells and causes a deficiency. Also associated with alcoholism.

30
Q

Vitamine C

A

Ascorbic acid. Scurvy. Helps conective tissue

31
Q

Folic acid

A

Folate. Most common deficiency in US. Helps purine and pyrimidine nucleotides.

32
Q

Vit D

A

Calciferol. Dangerous! Too low and get ricketts and osteomalacia. Excess with sarcoidosis. Most toxic of the vitamins

33
Q

Vitamine E

A

Tocopherol. Easy. The least toxic.

34
Q

Vitamin A

A

Retinol. Awful. Deficiency causes night blindness and bitots spot if low. Used to make rhodopsin.

35
Q

Vitamin K

A

Used for clotting.

36
Q

Copper

A

Get deposits with wilsons dz and kaiser fletcher ring. Also get sunflower cataracts. Wilson also called hepatolenticular degeneration.

37
Q

zinc

A

Used to DNA synthesis

38
Q

pyrimide dimers

A

made by two thymines on same strand. Caused by UV B.

39
Q

DNA has ___ with RNA has ___

A

T and U

40
Q

How to remember what each blot does

A
Sunny Day (south = DNA)
No Rain (north = RNA)
Why not Picnic (west=prot)
41
Q

Diseases that lead to early cataracs

A

MAD wilson. Myotonic dystrophy, atopic dermatitis, diabetes.

42
Q

The calories in proteins, carbs, and lipids

A

4,4,9