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NBEO Part 1 > Immunology > Flashcards

Immunology Flashcards

1
Q

Antigen Presenting Cells

A

Macrophages, Monocyte, Neutrophiles, Eosinophils, Basophils

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2
Q

Eosinophils

A

Parasitic and allergic reactions

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3
Q

Which APC is not phagocytic

A

Basophils

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4
Q

Which APC is most common

A

Neutrophils

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5
Q

Laugerhan

A

Macrophages in the skin

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6
Q

T-cells

A

Specific lymphocytes. Divide into Helper (CD4) and T cytotoxic (CD8)

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7
Q

B-cells

A

Specific lymphocytes. Make plasma cells which make AB.

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8
Q

Natural Killer Cells

A

Non specific lymphocytes. Do not need APC.

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9
Q

FAB portion of AB

A

bind antigens. Has a light and heavy chain

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10
Q

FC potion of AB

A

compliment and constant portion

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11
Q

Kupffer cells

A

APC in the liver

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12
Q

Non specific Immunity

A

Natural killer, interferon, Compliment (IgG, IGA, IGM)

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13
Q

What is the first thing to arrive with infection

A

Neutrophils (PMN)s.

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14
Q

What makes pus (suppuration)

A

PMNs

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15
Q

Which cells are PMNs

A

BEN. Basophils, neutrophils, eosinophils.

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16
Q

What do PMNs release

A

Granulocytes full of proteolytic enzymes that break down antigens

17
Q

Interferon

A

Nonspecific and increased in viral infections

18
Q

Beta interferon

A

Used for MS

19
Q

Alpha Interferon

A

Used for Hepatitis C.

20
Q

What does complement pathway do

A

CODD. Chemotaxis of neutrophils and macrophages, Opsonization, Degranulation of mast cells, direct lysis of bacteria

21
Q

Classic Complement pathway

A

GM motors. IgG, IGM.

22
Q

Alternative complment pathway

A

IgA and bacterial endotoxins.

23
Q

In laments terms what is Specific immunity

A

T cells telling B cells to make specific AB

24
Q

Where are B and T lymphocytes made

A

Bone

25
Q

Where do T lymphocytes mature

A

thymus

26
Q

where do B lymphocytes mature

A

Bone marrow

27
Q

Steps of Specific immunity

A

APC, Antigen must match, Receptors must match

28
Q

T helper cell has what receptor and who do they match

A

CD4 and match MHC II

29
Q

T killer cells have what receptor and who do they match

A

CD8 and match MHC I

30
Q

What happens after Macrophage matches with T-helper cell?

A

Sends IL-1 to T helper cell. Then T-helper cell sends IL-2 to B cells to create Ab

31
Q

When do Killer T cells work

A

Viral infections

32
Q

What does restates do?

A

Stops new release of IL2

33
Q

Type 4 hypersensitivty

A

Mediated by T killer cells.

34
Q

Haptin

A

Happens with Type 4 and T killer. SO small must bind protein for a reaction.

35
Q

Who do we order ANA for?

A

Lupus or other autoimmune.

NBEO Part 1 (17 decks)

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