Chapter 31/32

Question 1

Sulfonamides

Answer 1

• bacteriostatic

- inhibit folic acid synthesis for bacteria

Question 2

antitubercular drugs

Answer 2

single drug: resistance occurs
multidrug: 6-9 months, less resistance
Inhibit cell wall synthesis

Question 3

Antitubercular drugs

Answer 3

isoniazad, streptomycin, rifampin, ethambutol

Question 4

Antifungal drug group

Answer 4

• polyenes
• azoles
• antimetabolic
• antiprotozoals
• echinocandins

Question 5

Polyenes

Answer 5

Action: binds to fungal cell membranes

Question 6

Amphotercin B

Answer 6

• fungistatic/cidal

- Polyene

Question 7

Nystatin

Answer 7

Polyene
increases permeability of fungal cell membrane
fungicidal/static

Question 8

Azoles

Answer 8

Diflucan

-oral, IV, vaginal, topical

Question 9

Antimetabolites

Answer 9

selectively penetrates the fungal cell and disrupts fungal DNA and RNA synthesis

Question 10

Echinocandins

Answer 10

IV

inhibit biosynthesis of cell wall and interferes with growth and reproduction

Question 11

Peptides used as antibacterials

Answer 11

• Polymyxins

- Bacitracin

Question 12

Polymyxin

Answer 12

slow IV

• bacteriocidal by interfering with cell membrane of bacterium
• mostly gram -

Question 13

Bacitracin

Answer 13

• inhibits cell wall synthesis and damages the cell wall membrane
• static/cidal
• IM, topical

Question 14

Metronidazole

Answer 14

impairs DNA function

-mostly used for GI bacteria