Insulins, Thyroids, Pituitary/Adrenal Flashcards

1
Q

Rapid Acting Insulins

A

Aspart (Novolog)
Lispro (Humalog)
Glulisine (Apidra)

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2
Q

Intermediate Acting Insulins

A

Neutral Protamine Hagedorn (NPH)

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3
Q

Long Acting Insulins

A

Glargine (Lantus)
Detemir (Levemir)
Toujeo
Degludec (Tresiba)

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4
Q

Insulin Side Effects

A

Hypoglycemia
Weight Gain
Lipohypertrophy
Lipoatrophy

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5
Q

Insulin Injection Sites

A

Upper arms
Anterior/lateral aspects of the thigh
Buttocks
Abdomen (except 2 inch radius around navel)

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6
Q

Conditions that raise serum T4, T3 and TBG

A

Pregnancy
Infectious/chronic active hepatitis
HIV infection

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7
Q

Conditions that lower serum T3, T4 and TBG

A

Genetic factors
Acute and chronic illness
Glucocorticoids

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8
Q

Medications that affect thyroid function

A

Lithium
Iodine
Radiographic contract agents

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9
Q

Hypothyroid Drugs

A

Levothyroxine
Liothyronine
Thyroid USP (Armour Thyroid)

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10
Q

Drug Interactions with levothyroxine

A
Estrogens
Ca, Mg, Fe
Rifampin
Amiodarone
Iodine
Coudamin
Digoxin
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11
Q

Hypothyroid Drug ADRs

A

Palpitations
Insomnia
Nervousness

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12
Q

Hyperthyroid Drugs

A

Methimazole
Propylthiouracil
Beta blockers (propranolo, atenolol, metoprolol, nadolol)

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13
Q

Hyperthyroid Drugs ADRs

A

Rash
GI Upset
Arthalgias
HA

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14
Q

Treatment of Thyroid Storm

A

In order of effectiveness:
Propylthiouracil
Methimazole
Propranolol

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15
Q

Dopamine Agonists

A

Tx of Hyperprolactinemia
Cabergoline (Dostinex)
Bromocriptine (Parlodel)

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16
Q

Dopamine Agonists ADRs

A

Dizziness, HA, nausea

17
Q

Acromegaly Treatment

A

Dopamine Agonists
Somatostatin analogues
GH receptor antagonists

18
Q

Somatostatin Analogues

A
Acromegaly Tx
Octreotide (Sandostatin)
Lanreotide autogel (Somatuline)
19
Q

Somatostatin Analogues ADRs

A

Diarrhea
Abd. cramps
Flatulence

20
Q

GH Receptor Antagonist

A

Acromegaly Tx

Pegvisomant (Somatuline)

21
Q

Pegvisomant ADRs

A

N/D, injection site pain

22
Q

GH Deficiency Tx

A

Somatropin

23
Q

Somatropin ADRs

A

Intracranial tumors, intracranial hypertension, diabetic retinopathy

24
Q

ADH Deficiency (Diabetes Insipidus) Tx and ADRs

A

DDAVP (desmopressin)

ADRs: Nausea, HA, abd. cramps

25
Q

Pheochromocytoma Tx and ADRs

A

Phenoxybenzamine (use while awaiting surgery)

ADRs: hypotensioin, tachycardia, erectile dysfunction

26
Q

Adrenal Insufficiency Tx

A

Cortisol

27
Q

Hypoparathyroidism Tx

A
Calcium Gluconate (IV)
Vitamin D (Rocaltrol)
Oral Calcium
Calcitriol
Thiazide diuretics
Natpara
28
Q

Calcium Gluconate ADRs

A

Hypoparathyroid (hypocalcemia) tx

Tingling, heat sensation, chalky taste

29
Q

Calcitriol ADRs

A

Hypoparathyroid (hypocalcemia) tx

Hypercalcemia, hypercalciuria, vitamin D intoxication

30
Q

Natpara ADRs

A

Hypoparathyroid (hypocalcemia) tx

N/V/D