Eggena 22-1

Question 1

In gluten intolerance

Answer 1

gluten is toxic to intestinal epithelial cells, which are sloughed off into the intestinal lumen.

Question 2

celical disease

Answer 2

a malabsorption syndrome in which the small intestine cannot absorb and digest proteins, fats and starches.

Question 3

steatorrhea

Answer 3

the presence of excess fat in stool.

Question 4

the fat loss in stool is due to

Answer 4

a problem in fat digestion and absorption. Fat digestion requires an adequate supply of bile for emulsification of lipids.

Question 5

bile is lacking in persons with sprue because

Answer 5

it is not reabsorbed as usual from the terminal ileum and recycled via enterohepatic circulation in the duodenum.

Question 6

because injured mucosal cells fail to secrete

Answer 6

CCK and secretin, biel is not released normally from the gall bladder, and lipases are not secreted from the pancreas to promote fat digestion.

Question 7

fat digestion and absorption in sprue is more severely impaired than

Answer 7

carbohydrate or protein digestion.

Question 8

pancreatic amylase, which depends on

Answer 8

normal secretin (CCK) release, is also deficient in sprue, as are enzymes for carbohydrates in the brush border of mucosal cells.

Question 9

steatorrhea had diminished absorption of

Answer 9

fat soluble vitamins (A and D) and repeated bouts of diarrhea had diminished absorption of water soluble vitamins and airon

Question 10

anemia is caused by a deficient absorption of

Answer 10

vitamin 812 (cobalamin) and folic acid

Question 11

decreased transferrin was caused by

Answer 11

a decrease in serum iron concentration and by an increase in the total amount of circulating transferrin.

Question 12

abnormal absorption of cobalamin (vitamin 812) could have resulted from

Answer 12

injured cells in the terminal ileum from sprue or from absence of intrinsic factor due to atrophied parietal cells in the stomach.

Question 13

the malabsorption of cobalamin was due to

Answer 13

mucosal defects in absorption

Question 14

a deficiency of iron, folic acid and vitamin 812 causes

Answer 14

glossitis (swollen tongue)

stomatitis (inflamed mouth)

cheliosis (cracked lips)

Question 15

vitamin C deficiency causes

Answer 15

loosing of the teeth and bleeding of the gums.

Question 16

vitamin K depletionon occurs early because

Answer 16

vitamin K stores are small.

Question 17

vitamin A deficiency causes

Answer 17

causes limited night vision and dry/thickened skin

Question 18

peripheral neuritis results from

Answer 18

deficiencies in thiamin, cobalamin and folic acid

Question 19

hypoproteinemia decreases

Answer 19

plasma colloid osmotic pressure, while thiamin deficiency leads to relaxation of arteriolar smooth muscle.

Both contribute to edema.