Ketone bodies Flashcards
1
Q
Where are ketone bodies made?
A
in the liver mitochondria
2
Q
name the 3 ketone bodies
A
Acetone
Acetoacetate
β-Hydroxybutyrate
3
Q
What does increasing levels of ketone bodies lead to?
A
ketoacidosis
4
Q
how is the production of ketone bodies regulated?
A
the insulin:glucagon ratio
if low, ketone bodies produced
5
Q
How can you check if someone is in ketoacidosis?
A
the smell of acetone on their breath
6
Q
How are ketone bodies produced? (two precursors)
A
FAs–>Acetyl CoA–>Ketone bodies
7
Q
How are ketone bodies used for energy?
A
Ketone bodies–>acetyl CoA in tissue
Acetyl CoA used for energy
8
Q
In starvation, what are ketone bodies used for, to do with the brain?
A
Spare glucose
9
Q
Two situations where ketone bodies may be produced?
A
untreated diabetes and starvation
