Fungi Flashcards

1
Q

What are the three types of fungi?

A

Moulds
Yeasts
Mushrooms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How do fungi survive?

A

Secrete hydrolytic enzymes

They are either saprophytic or parasitic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Fungi are anaerobic. True or false?

A

False - usually aerobic, some are facultative anaerobes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Fungi cell wall is composed of 80-90% polysaccharide. True or false?

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are good selective targets for drugs in the cell wall of a fungi?

A

Chitin - found in moulds

Mannans - found in yeast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

In the cell membrane fungi have cholesterol. True or false?

A

False - they have ergosterol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Why is ergosterol a good target for drugs?

A

Humans don’t have ergosterol in the cell membrane, they have cholesterol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Yeasts are unicellular fungi. True or false?

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Yeast can only divide sexually. True or false?

A

False - they can divide sexually (spore formation) and asexually (budding)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the shape of yeast?

A

Spherical, oval or cylindrical in shape

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the shape of mould?

A

Consist of branched thread like filaments called hyphae which form mycelium. They are multinucleate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Moulds can be septate or coenocytic. What is the difference?

A

Septate - have cross walls

Coenocytic - continuous cytoplasm with no cross walls

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Fungi have two morphological forms. What are they and why are they advantageous?

A

Yeast
Mycelial
Reproduction more rapid under adverse environmental stress and provides a competitive advantage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

In fungi, asexual reproduction produces offspring that are genetically identical to the “parent”. True or false?

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

During sexual reproduction, mixing of genetic material occurs so offspring exhibit traits of both parents. True or false?

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Spores are all the same in all moulds. True or false?

A

False - they depend on species e.g. some have ascospores and some have basidiospores

17
Q

Yeasts are important in fermentation and genetic engineering. True or false?

A

True

18
Q

How are mycoses classified?

A

Superficial mycoses
Subcutaneous mycoses
Systemic mycoses

19
Q

What are three classes of ergosterol inhibitor drugs?

A

Polyenes
Azoles
Allyamines

20
Q

How do polyenes work?

A

Bind ergosterol and disrupt membrane function

21
Q

How do azoles work?

A

Inhibit ergosterol biosynthesis

22
Q

How do allyamines work?

A

Inhibit ergosterol biosynthesis

23
Q

How do polyoxins work?

A

Inhibit chitin biosynthesis