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Pharmacology > Specific antidotes > Flashcards

Specific antidotes Flashcards

1
Q

Acetaminophen

A

N-acetylcysteine (replenish glutathione)

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2
Q

Salicylates

A

NaHCO3 (alkalinize urine), dialysis

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3
Q

Amphetamines

A

NH4Cl (acidify urine)

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4
Q

Organophosphates

Acetylcholinesterase inhibitors

A

Atropine + pralidoxime

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5
Q

Antimuscarinic

Anticholinergic agents

A

Physostigmine salicylate, control hyperthermia

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6
Q

Beta-blockers

A

Glucagon

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7
Q

Digitalis

A

Normalize K+, Lidocaine, Anti-dig Fab fragments, Mg2+ (KLAM)

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8
Q

Iron

A

Deferoxamine, deferasirox

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9
Q

Lead

A

CaEDTA, dimercaprol, succimer, penicillamine

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10
Q

Mercury, arsenic, gold

A

dimercaprol (BAL), succimer

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11
Q

Copper, arsenic, gold

A

penicillamine

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12
Q

Cyanide

A

Nitrite + thiosulfate, hydroxocobalamin

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13
Q

Methemoglobin

A

Methylene blue, vitamin C

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14
Q

Carbon monoxide

A

100% O2, hyperbaric O2

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15
Q 
Methanol
Ethylene glycol (antifreeze)
A

Femopizole > ethanol, dialysis

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16
Q

Opioids

A

Naloxone/naltrexone

17
Q

Benzodiazepines

A

Flumazenil

18
Q

TCAs

A

NaHCO3 (plasma alkalinization)

19
Q

Heparin

A

Protamine

20
Q

Warfarin

A

Vitamin K, fresh frozen plasma

21
Q

tPA
streptokinase
urokinase

A

Aminocaproic acid

22
Q

Theophylline

A

Beta-blocker

23
Q

Alkali agents (Batteries, drain cleaners, detergents)

A

milk, H2O, NPO (prevent further esophageal erosions)

24
Q

Quinidine (Torsades de pointes)

A

IV Mg2+

Pharmacology (8 decks)

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