6.1 RBC Morphological abnormalities Flashcards by Miguel Acosta

Q

Term for abnormal variation in cell size

A

Anisocytosis

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Q

Anisocytosis is based on cell Diameter and MCV

T or F

A

T

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Q

Normal value for normocytic in cell diameter??

A

6-8 um

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Q

Normal value for normocytic in MCV??

A

80-100 fL

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Q

Microcytic in cell diameter and MCV

A

<6

<80

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Q

MAcrocytic in cell diameter and MCV

A

> 8 um

> 100 fL

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Q

Term for variation in hemoglobin content of RBCs?

A

Anisochromia

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Q

Anisochromia is based on central pallor and MCHC

T or F

A

T

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Q

Normal value for Normochromic in central pallor?

A

1/3 diameter

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Q

Normal value for Normochromic in MCHC?

A

32-36%

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Q

Hypochromic in terms of Central pallor

A

> 1/3 of diameter of RBC

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Q

Hyperchromic in terms of Central pallor

A

Absent of <1/3 of diameter of RBC

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Q

Hypochromic in terms of MCHC

A

<32 MCHC

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Q

Hyperchromic in terms of MCHC

A

> 36%

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Q

Abnormal variation in RBC shape

A

Poikilocytosis

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Q

Deep staining large oval cell

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

A

a

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Q

Few Irreglarly spaced projections of varying length and width (Irregular and asymmetic

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

A

c

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Q

RBC with blunt or pointed, short projections that are evenly spaced (Symmetric)

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

A

d

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Q

Associated with Vit B12 deficiency and Folic acid deficiency

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

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A

a

Q

Associated with Severe liver disease, Abetalipoproteinemia

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

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A

c

Q

Associated with Mcleod Syndrome

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

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A

c

Q

Associated with Uremia and Pyruvate kinase deficiency

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

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A

d

Q

Associated with Autoimmune hemolytic anemia and severe burns

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

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A

b

Q

Associated with Bassen-Kornzweig Syndrome

a. Macroovalocyte
b. Spherocyte
c. Acanthocyte
d. Echinocyte

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A

c

In Acantocytes, Abetalipoproteinemia is the absence of LDL while Mcleod syndrome is the weak expression of Kell antigens T or F

T

Also known as Thorn or spur cell a. Macroovalocyte b. Spherocyte c. Acanthocyte d. Echinocyte

c

Also known as Burr cell a. Macroovalocyte b. Spherocyte c. Acanthocyte d. Echinocyte

d

Also known as Bronze cell a. Macroovalocyte b. Spherocyte c. Acanthocyte d. Echinocyte

b

In Echniocyte, Uremia is the increase in blood urea and creatinine with symptoms of kidney disease T or F

T

If there is an increase in ure and creatinine but no kidney disease, this is a sign of?

Azotemia

Azotememia is an in vitro the resembles?

Crenated RBC

Hemoglobin concentrated in the center and around the periphery a. Target Cell b. Stomatocyte c. Elliptocyte d. Schistocyte

a

Narrow oval cells which shaped like an Egg-shaped or Cigar-shaped a. Target Cell b. Stomatocyte c. Elliptocyte d. Schistocyte

c

Slit-like (mouth-like) area of central pallor a. Target Cell b. Stomatocyte c. Elliptocyte d. Schistocyte

b

Fragmented RBCs caused by rupture in peripheral circulation a. Target Cell b. Stomatocyte c. Elliptocyte d. Schistocyte

d

Associated with Acute alcoholism and Rh Null a. Target Cell b. Stomatocyte c. Elliptocyte d. Schistocyte

b

Associated with Thalassemia major and IDA a. Target Cell b. Stomatocyte c. Elliptocyte d. Schistocyte

c

Associated with Obstructive jaundice, HB C disease and Thalassemia a. Target Cell b. Stomatocyte c. Elliptocyte d. Schistocyte

a

Associated with Microangiopathic hemolytic anemia (MAHA) and severe burns a. Target Cell b. Stomatocyte c. Elliptocyte d. Schistocyte

d

MAHA may result to D__ Hemolytic uremic syndrome Thrombotic, Thrombocytopenic purpura

DIC

Also known as Codocyte, Mexican hat and Leptocyte a. Target Cell b. Stomatocyte c. Elliptocyte d. Schistocyte

a

Also known as Helmet cell, Keratocyte and RBC fragments a. Target Cell b. Stomatocyte c. Elliptocyte d. Schistocyte

d

Hemolytic uremic syndrome in MAHA is associated with what bacteria?

E. coli 0157:H7

Has single pointed extrnsion resembling tear drop or pear a. Dacryocyte b. Drepanocyte

a

Crescent-shaped cell; caused by crystallization of Hb S due to ↓ O2 tension a. Dacryocyte b. Drepanocyte

b

Associated with primary Myelofibrosis and Myeloblastic anemia a. Dacryocyte b. Drepanocyte

a

Associated with sickle cell anemia / Sickle cell-beta thalassemia a. Dacryocyte b. Drepanocyte

b