Microbiology Flashcards

1
Q

What is materia alba made up of? look like? How is it removed?

A
  1. Soft accumulation of salivary proteins, food debris.
  2. White Cheese-like accumulation
  3. Can be removed with water spray.
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2
Q

What is dental plaque made up of? Looks like? Removed?

A
  1. Composed of bacteria, salivary glycoproteins, polysaccarides.
  2. Clear, yellowish grayish substance
  3. Must be mechanically removed.
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3
Q

What are the red complexes that are associated with subgingival disease?

A

P. Gingivalis
T. forsythia
T. denticola

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4
Q

What are the characteristics of supragingival calculus?

A
  • Whitish yellow
  • Clay-like consistency
  • Easily detached
  • Found near salivary ducts
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5
Q

What are the characteristics of subgingival calculus?

A
  • Dark colored

- Hard, dense

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6
Q

What are the 4 forms of calculus (calcium phosphate) and where is it seen?

A
  1. Brushite. Found on recent/new calculus.
  2. Octa CP. On exterior layers
  3. Hydroxyapatite. Old calculus.
  4. Whitlockite. Subgingival calculus.
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7
Q

Is calculus an etiological agent of periodontitis?

A

No. I can be a secondary product, but is not the cause.

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8
Q

In initial lesions (stage I), Early lesion (stage II), and Established lesions (stage III), what cells predominate?

A

I. PMNs
II. Lymphocytes
III. Plasma cells

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9
Q

What does high RANKL levels indicate? High OPG?

A

RANKL= periodontitis

OPG=Healing phase.

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10
Q

Which cells predominate in chronic periodontitis?

A

Th2 cells and Plasma cells.

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11
Q

What is the stages of plaque formation?

A
  • Pellicle forms form glycoproteins
  • colonization by bacteria
  • Progressive buildup of plaque substances
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12
Q

Which bacteria forms a lot of interactions with other bacteria?

A

-Fusobacterium nucleatum
-S. oralis
S. sangulis

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13
Q

How is sessile organisms more resistant to antimicrobials?

A

Protection by thick biofilm.

Phenotypic shift in behavior during biofilm mode.

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14
Q

Which are the predominant supragingival bacteria?

A
  • Actinomyces
  • Neisseria mucosa
  • Capnocytophaga
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15
Q

Which are the predominant microbiota in subgingival plaque?

A
  • Strep
  • Actinomyces
  • Eubacterium
  • Veillonella
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16
Q

What increases with increased disease in the mouth?

A

Gram negative rods, motile species, and spirochets.

17
Q

Inflammatory mechanisms can be divided into what two sources?

A
  1. Derived from subgingival microbiota

2. Derived from the host immune-inflammatory response.

18
Q

Alveolar bone resorption stops at which distance between bone and bacteria in pocket?

A

2.5 mm