Cancer meds

Question 1

Calcitonin

Answer 1

To lower calcium levels

Question 2

Pamidronate

Answer 2

Lower calcium levels

Question 3

Zolendronic acid

Answer 3

Lower calcium levels

Question 4

Antimetabolites

Answer 4

Interferes with cells RNA & DNA - works when cells are dividing
Methotrexate

Question 5

Antitumor Antibiotics

Answer 5

Attach themselves to tumor-specific antigens thereby increasing immune response to tumor cell

Question 6

Antimitotics

Answer 6

Interferes with cell division at microtubule level

Taxol (Paclitaxol) Used to treat breast cancer that has metastasized, Kaposi’s sarcoma. Given with benadryl and steroids as causes allergic reaction

Question 7

Alkylating Agents

Answer 7

Works on DNA to stop cell reproducing. Kills cells in all phases

Question 8

Topoisemerase Inhibitors

Answer 8

This inhibits the enzyme topoismerase (responsible for coiling and uncoiling DNA in cell division) Kills all cells dividing

Question 9

Drugs for hypercalcemia

Answer 9

Calcitonin
Pamidronate
Zolendronic Acid

Question 10

Drugs for Neutropenia

Answer 10

Filgrastim

Interleukin 2

Question 11

Drug for Thrombocytopenia

Answer 11

Interleukin 11

Question 12

Antiemetic drugs (Serotonin Antagonists)

Answer 12

Serotonin Antagonists - Block 5-HT3 receptors in brain
Ondansetron (Zofran)
Granisetron - Kytril
Dolasetron (Anzemet)
Palonosetron (Aloxi)

Question 13

Antiemetic Drugs - Benzodiazapines

Answer 13

Lorazepam (Ativan)

Question 14

Antiemetic drugs (corticosteroids)

Answer 14

Dexamethasone - decreases swelling in brain

Question 15

Antiemetic drugs -Prokinetic agents

Answer 15

Reduce N&V by blocking dopamine

Question 16

Antiemetic drugs - Neurokinin Receptor Antagonist

Answer 16

Block Substance P neurokin receptor - when used with corticosteroids and serotonin antagonist - both acute & delayed N&V are controlled