RBC Disorders Flashcards

1
Q

Rule of 3

A

HGB x 3 = HCT +/- 3

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2
Q

MCV

A

RBC size

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3
Q

HGB ranges

A

women- 12

men- 13.5

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4
Q

Hypochromic / Hyperchromic

A

low / high MCHC

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5
Q

MCHC

A

mean cell HGB concentration

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6
Q

Reticulocytes

A

immature circulating RBCs

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7
Q

Normocytic

A

MCV 80 - 100

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8
Q

Microcytic

A

MCV <80
iron deficiency
thalassemia

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9
Q

Macrocytic

A

MCV >100

B12 and folate deficiency

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10
Q

Causes of Anemia

A

blood loss
impaired RBC production
accelerated RBC destruction

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11
Q

Iron Deficiency Anemia

A

most common
low ferritin levels
chronic blood loss somewhere

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12
Q

Most common cause of microcytic anemia

A

Iron deficiency

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13
Q

Increased Reticulocytes indicates….

A

hemolysis or blood loss

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14
Q

Intrinsic Factor

A

needed to absorb B12

if missing will have B12 deficiency- macrocytic anemia

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15
Q

Time to depletion in folate deficiency

A

3 months

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16
Q

Time to depletion in B12 deficiency

A

3 years

17
Q

G6PD Deficiency

A

X linked

lysis triggered by consumption of fava beans (favism)

18
Q

Drugs to avoid in G6PD Deficiency

A

NSAIDS
antimalarials
sulfa drugs

19
Q

B-Thalassemia

A

decreased production of HGB B-chain

20
Q

a-Thalassemia

A

decreased production of HGB a-chain

21
Q

Places where Thalassemia is most prevalent

A

Mediterranean- Italy and Greece
Middle East
SE Asia
S China

22
Q

Thalassemia causes what type of anemia

A

microcytic, hypochromic anemia