Immunology 1 Flashcards

1
Q

What does the immune system do?

A

identify and eliminate microorganisms as well as other harmful substances

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2
Q

Give 3 reasons new infectious diseases emerge.

A

Global village, population growth, changes in human behaviour

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3
Q

What are the physiological factors of skin that make them a good first line of defence?

A

low pH 5.5 and low oxygen tension

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4
Q

What is the most important barrier to infection?

A

skin

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5
Q

Name 3 tracts where mucous is found

A

GI, resp and urogenital

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6
Q

What does mucous secrete?

A

IgA

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7
Q

What sort of relationship to humans does commensal bad have?

A

symbiotic

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8
Q

What in the mucous is important in preventing bad?

A

proteins and peptides

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9
Q

Give 2 examples of breaching of constitutive bacteria

A

IV line, catheter

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10
Q

What are cytokines?

A

diverse collection of small proteins and peptides

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11
Q

What is the key role of cytokines?

A

co-ordinate immune system

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12
Q

What cell produces antibodies?

A

B cells

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13
Q

What is an antigen?

A

any cell that can produce an immune response

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14
Q

What do helper T cells do?

A

regulate immune system

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15
Q

What to cytoxic T cells do?

A

Kill virally infected body cells

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16
Q

What are natural killer cells?

A

large granular lymphocytes

17
Q

What do natural killer cells do?

A

detect and kill tumour & virally infected cells

18
Q

Where do Mast cells reside?

A

in tissues

19
Q

Where do you find eosinophils and basophils?

A

blood

20
Q

What do mast cells, eosinophils and basophils release?

A

histamine

21
Q

Name the 3 phagocytes

A

monocytes, macrophages, neutrophils

22
Q

Which one of the phagocytes doesn’t circulate in blood?

A

macrophages

23
Q

What are dendritic cells important for?

A

antigen presentation