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Block 3 Pharmacology > Magnesium Trisilicate > Flashcards

Magnesium Trisilicate Flashcards

1
Q

Class

A

Antacid

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2
Q

Actions

A

Neutralise the acid directly by raising the pH in the
stomach. Also inhibits peptic enzymes by adsorbing
pepsin. Insoluble powder that reacts slowly with
gastric juice which forms magnesium chloride and
colloidal silica

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3
Q

Mechanism of Action

A

?

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4
Q

Clinical Use

A

Dyspepsia
Symptomatic relief in
peptic ulcers or
oesophageal refluc

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5
Q

Adverse effects

A

Diarrhoea
Belching
Silica based renal
stones

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6
Q

how does Aluminum hydroxide aide the healing of peptic ulcers?

A

binds growth factors, possibly serving to deliver growth factors to injured mucosa.

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7
Q

how do Antacids aide the healing of peptic ulcers?

A

promote angiogenesis in injured mucosa and bind bile acids and also inhibit peptic activity

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8
Q

how do Heavy metals aide the healing of peptic ulcers?

A

suppress, but generally do not eradicate, H. pylori

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Block 3 Pharmacology (26 decks)

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