lecture 6 renal acid-base balance Flashcards

1
Q

what maintains pH

A

kidneys

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2
Q

what is an acid

A

a substance which donates protons

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3
Q

what is a base

A

a subastance that accepts a proton

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4
Q

in vessels where is pH higher

A

arterial

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5
Q

which vessel is more acidic and why

A

veins

carrying more CO2 which dissolves in water to make carbonic acid

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6
Q

what are the three things which look after H+ conc in the blood

A

chemical buffer
respiratory center
renal system

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7
Q

what is the bicarbonate buffer system

A

hydrogen and bicarbonate make carbonic acid

carbonic acid splits into CO2 and water

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8
Q

when you excersize why do you breathe quicker

A

producing more CO2

want to restore pH

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9
Q

inside blood cells what can the hydrogen ions become bound to

A

haemoglobin

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10
Q

what are the cells responsible for the water sodium balance in the CD balance

A

principal cells

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11
Q

what hormone do principal cells respond to

A

ADH

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12
Q

what affect does ADH have on principal cells

A

water resorption by aquaporins

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13
Q

what are the acid base balance cells in CD

A

intercalated cells

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14
Q

where is bicarbonate reabsorbed

A

PCT

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15
Q

how do the H and bicarbonate enter the intercalated cell

A

as CO2 and water

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16
Q

from the intercalated discs what happens to the hydrogen ions and bicarbonate ions

A

hydrogen back into filtrate

bicarbonate into interstitial fluid

17
Q

how do we introduce new H+

A

in diet

18
Q

how is new bicarbonate produced in the tubule

A

glutamine is metabolised into bicarbonate and NH4

19
Q

what happens to NH4 produced in the tubule

A

excreted in urine

20
Q

what is metabolic alkalosis caused by

A

vomiting