amtiemetics Flashcards
1
Q
name the main one
A
metoclopramide
2
Q
what type is it
A
D2 receptor antagonist
3
Q
name another
A
cyclizine
4
Q
what other properties does cyclizine have
A
anti-cholinergic
5
Q
uses
most commonly?
A
prophylaxis and treatment of nausea and vomiting in a range of conditions but most commonly for reduced gut motility
6
Q
MOA
A
nausea triggered by
- gut irritation
drug motility - motion and vestibular disorders
7
Q
contraindications
A
young adult, children
obstruction –> perforation
8
Q
possible interactions
A
anti-psychotics
dopaminergic agent antagonists (Parkinson treatment)
9
Q
adverse effects
A
diarrhoea is the most common side effect
metoclopramide ca include extra pyramidal syndromes such as movement abnormalities and acute dystonic reactions
