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Host & Defense > Intro to Virology > Flashcards

Intro to Virology Flashcards

1
Q

How is one exposed to Pepper Mild Mottle Virus?

A

Water, Feces or urine

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2
Q

8% of the human genome is made up of…?

A

endogenous retroviral sequence

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3
Q

What is the protein seath that protects the genome called?

A

Capsid

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4
Q

What are the 3 types of capsids?

A

Helical
Icosahedral
Complex

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5
Q

the protein layer between the capsid and envelope of a virus is called?

A

Tegument or matrix protein

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6
Q

Baltimore Classification group I

A

DNA (+/-)

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7
Q

Baltimore Classification group II

A

DNA (+)

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8
Q

Baltimore Classification group III

A

RNA (+/-)

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9
Q

Baltimore Classification group IV

A

RNA (+)

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10
Q

Baltimore Classification group V

A

RNA (-)

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11
Q

Baltimore Classification group VI

A

RNA (+)

requires reverse transcription

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12
Q

Baltimore Classification group VII

A

DNA (+/-)

requires reverse transcription

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13
Q

Hepadnaviridae has what kind of viral genome structure?

A

Circular

Gapped

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14
Q

What are the 4 types of Viral Genome Structuce

A

Linear
Circular
Gapped
Segmented

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15
Q

Influenza has what kind of viral genome structure?

A

Segmented

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16
Q

What makes up the eclipse phase?

A

Adsorption
Intimate Contact
Penetration and Uncoating

17
Q

What is burst?

A

Lytic cycle releasing the virions

18
Q

How does Fusion Penetration work?

A

envelope fuses with cell membrane then ejects virus into the cell cytoplasm

19
Q

How does Viropexis work?

A

An envoloped virus creates a capsule for it self (reverse budding) and then enters the cytoplasm via fusion with the capsule.

20
Q

How do encapsulated viruses (no envelope) enter the cytoplasm?

A

via clathrin-mediated endocytosis (Most common method)

21
Q

What is susceptibility?

A

whether a cell expresses the proper receptors for a virus to gain entry to the cell

22
Q

What is Permissivity?

A

If the cell contains the proper enzymes for viral replication

23
Q

What do cells need to become infected?

A

They need to be both susceptible and permissive.

24
Q

What is a retroviruse?

A

RNA viruses that reproduce through a DNA intermediate

25
Q

Define a Provirus

A

the genetic material of a virus as incorporated into, and able to replicate with, the genome of a host cell.

26
Q

What are 3 impacts on mutation rate?

A

Genome size
Replication rate
Host Conditions

Host & Defense (15 decks)

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