Multifocal CNS Disease

Question 1

Which neoplasia like to metastasize to CNS?

Answer 1

1. Lymphoma
2. Melanoma
3. Hemangiosarcoma
4. Urogenital carcinoma
5. Thyroid carcinoma

Question 2

What neoplasia is multifocal to diffuse in the CNS?

Answer 2

Lymphoma
Multiple myeloma
Histiocytic sarcoma

Question 3

What is the treatment for GME?

Answer 3

Steroids

Immunosupressants

Question 4

Necrotizing meningoencephalitis

Answer 4

Pug, maltese, pomeranian, chihuahua

Young to middle-aged

Acute, progressive

Causes forebrain dysfunction (mentation changes, seizures, cervical pain)

Question 5

Necrotizing leukoencephalitis

Answer 5

Yorkie, frenchie, chihuahua

Chronic, progressive

Usually fatal

Multifocal neuro signs (cerebrum and brainstem)

Question 6

Treatment for MUE

Answer 6

Steroids

Immunosupressants

Question 7

Myoclonus is a clinical sign of what disease?

Answer 7

Distemper

Question 8

Severe meningeal enhancement on MRI of cat may be indicative of what disease?

Answer 8

FIP

Question 9

FIP

Answer 9

35% of cats are neuro

Ataxia, nystagmus, seizures, obtundation

Anti-coronavirus IgG titer on CSF

High serum total protein

CSF: neutrophilic pleocytosis

Question 10

Treatment for toxoplasma?

Answer 10

Clindamycin (don’t give TMS to cats)