Chapter 12- DNA and RNA Flashcards

1
Q

What was the result ofGriffith’s experiment?

A

Scientists realized that since the ability to cause disease was inherited by the transformed bacteria’s offspring the transforming factor might be a gene

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2
Q

What did Avery discover

A

That DNA stores and transfers DNA from one generation to the next

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3
Q

What did Hershey and Chase work With in their famous experiment?

A

Bacteriophage

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4
Q

Who proved the DNA composition

A

Chargoff

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5
Q

What is DNA composed of

A

Deoxyribose sugar, phosphate group, and nucleic acids: adenine, guanine, cytosine, and thymine

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6
Q

Who produced an x-ray shadow image of DNA

A

Franklin

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7
Q

What two men were responsible for discovering the shape of DNA?
What did they call the shape?

A

Watson and Crick

Double Helix

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8
Q

What is DNA like I’m prokaryotic cells

A

In one continuous loop in the cytoplasm

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9
Q

What is chromatin

A

DNA when it’s all uncoiled

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10
Q

What are histones

A

The circular protein that DNA coils around.

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11
Q

When the DNA coils around the histones what is that structure called

A

Nucleosome

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12
Q

What is the function of DNA polymerase?

A

It acts like a pair of scissors that cuts the DNA in half. It also double checks and makes sure that the guanines match with The cytosines and the adenine match with the thymine

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13
Q

mRNA

A

Messenger RNA

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14
Q

What is mRNA’s job

A

It takes the mold of what the DNA gives it, then it leaves the nucleus, goes out into the cytoplasm, then it goes through the ribosomes

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15
Q

tRNA

A

Transfer RNA

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16
Q

What does tRNA do

A

Picks up amino acids and brings codon into ribosomes

17
Q

Codon

A

Group of three base pairs

18
Q

Two main parts of protein synthesis

A

Transcription

Translation

19
Q

Polypeptide

A

A grouping of amino acids (protein)

20
Q

A codon has how many nucleotides

A

3

21
Q

3 nucleotides make an

A

Amino acid

22
Q

Chains of amino acids

A

Proteins

23
Q

What is an anticodon

A

From transfer RNA and matches to the codon on the mRNA

24
Q

Point mutations

A

Created when one specific amino acid grouping is wrong in the sequence. (They occur at one point)

25
Q

Frameshift mutations

A

The reading frame of the genetic message moves one codon space. They often destroy the functionality of the produced proteins

26
Q

Chromosomal mutations

A

Change the location of the genes on the chromosomes

27
Q

The four types of chromosomal mutations

A
  1. Deletion; missing a chunk of a chromosome so it can’t do its job properly
  2. Duplication; accidental duplication of DNA affects it’s ability to make protein etc
  3. Inversion; things move to the other side of the chromosome
  4. Translocation; something moves from one chromosome to another (screws up two chromosomes)
28
Q

Cytogenetics

A

When people take cells from a baby or umbilical cord and sequence the chromosomes to check for defects

29
Q

Polyploidy

A

The condition in which an organism has an extra set of chromosomes