Translocations, markers Flashcards

1
Q

t(11;14)

A

mantle cell lymphoma

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2
Q

cyclin D1 activation (G1 to S phase)

A

mantle cell lymphoma

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3
Q

dry tap, splenomegaly, teardrop RBCs

A

myelofibrosis

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4
Q

t(9;22), BCR/ABL, philadelphia chromosome

A

CML

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5
Q

pautrier microabscesses

A

mycosis fungoides

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6
Q

CD5+

A

CLL

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7
Q

CD55 and CD59 (-)

A

paroxysmal nocturnal hemoglobinuria

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8
Q

elevated red cell mass indicates ________ erythrocytosis

A

absolute

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9
Q

chronic anemia seen in SLE and CLL and with certain drugs

A

warm autoimmune hemolytic anemia

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10
Q

t(8;14)

A

Burkitt lymphoma

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11
Q

c-myc activation

A

Burkitt lymphoma

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12
Q

t(15;17)

A

acute promyelocytic leukemia

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13
Q

trisomy 12

A

CLL/SLL

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14
Q

t(14;18)

A

follicular lymphoma

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15
Q

BCL-2 overexpression

A

follicular lymphoma

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16
Q

t(11;18)

A

marginal zone lymphoma, MALT