Pathology of Non-Melanocytic Tumours

Question 1

Which type of cancer will present as a flesh or bluish/red coloured nodule on the face, head or neck?

Answer 1

Merkel cell carcinoma

Question 2

Which skin condition is associated with horn cysts?

Answer 2

Seborrhoeic keratosis

Question 3

What is seborrhoeic keratosis due to?

Answer 3

Benign proliferation of keratinocytes

Question 4

Where is seborrhoeic keratosis most commonly found?

Answer 4

Ageing skin on face and trunk

Question 5

Which virus is associated with squamous cell carcinoma?

Answer 5

HPV

Question 6

Which type of basal cell carcinoma has prominent desmoplastic fibrous stroma?

Answer 6

Infiltrative

Question 7

What are desmoplastic fibrous stroma?

Answer 7

Fibrous tissues which grow around the tumour

Question 8

What is the term given to “a common precursor of squamous cell carcinoma found on sun exposed sites”?

Answer 8

Acitinic keratosis

Question 9

Peripheral palisading is associated with which condition?

Answer 9

Basal cell carcinoma

Question 10

Whar are peripheral palisades?

Answer 10

The pale space which separates the tumour from the inflammatory cells in basal cell carcinoma

Question 11

Which conditions can be precursors for squamous cell carcinoma?

Answer 11

Actinic keratosis

Bowen’s disease

Viral lesions

Question 12

Which layer of the skin is affected by benign seborrhoeic keratosis?

Answer 12

Epidermis

Question 13

Which condition has three main subtypes (nodular, superficial and infiltrative)?

Answer 13

Basal cell carcinoma

Question 14

Which skin condition can arise from an insect bite?

Answer 14

Dermatofibroma

Question 15

What is the name given to squamous cell carcinoma in-situ?

Answer 15

Bowen’s disease

Question 16

In which sex does Bowen’s disease most commonly affect?

Answer 16

Females

(on the lower leg)

Question 17

What is the appearance of Bowen’s disease?

Answer 17

Scaly patch or plaque with an irregular border

Question 18

Which condition has a raised “stuck on” appearance and is entirely benign?

Answer 18

Benign seborrhoeic keratosis

Question 19

In which area of the body is it most dangerous to have a basal cell carcinoma?

Answer 19

Near the eye

(can invade eye, an from there, the brain)