Anticoagulants & Supplements

Question 1

Unfractionated Heprin

Answer 1

Heparin
Anticoagulant
Blood thinner
Inactivation of thrombin & factor Xa
Active bleeding, short half life, unpredictability
Regular aPTT testing
Antidote is protamine sulfate

Question 2

Enoxaparin

Answer 2

Lovenox
Anticoagulant - low molecular weight
Blood thinner
Inactivates factor Xa
Active bleeding, no protein binding, renal dysfunction
Monitor renal function and platelets

Question 3

Warfarin

Answer 3

Coumadin
Anticoagulant - Vitamin K antagonist
Blood thinner
Inhibits synthesis of Vitamin K dependent clotting factors (II, VII, IX, X & Thrombin)
Bleeding, multiple drug interactions, constant monitoring of prothrombin and INR
Bleeding preparations before surgeries, watch diet and vitamin K intake

Question 4

Dabigatran

Answer 4

Pradaxa
Anticoagulant - Direct Factor Xa inhibitor
Blood thinner
Direct thrombin inhibitor
Bleeding, GI effects, dark stools
Bleeding, drug interactions, antidote is idarucizumab

Question 5

Rivaroxabin

Answer 5

Xarelto
Anticoagulant - Direct Factor Xa Inhibitor
Blood thinner
Factor Xa inhibitor
Bleeding
NO ANTIDOTE, less drug interactions, no labs to monitor

Question 6

Ferrous Sulfate

Answer 6

Iron
Nutritional supplement
Iron deficiency anemia
GI disturbances, nausea, constipation, change in stool color
Can be toxic at high levels, reduced absorption with antacids, interacts with vitamin c

Question 7

Iron Dextran

Answer 7

Iron Dextran
Parenteral Iron preparation
Iron deficiency anemia
Anaphylaxis, hypotension, circulatory failure, cardiac arrest
Start with test doses of 25mg over 5 minutes

Question 8

Cyanocobalamin

Answer 8

Vitamin B12
Nutritional deficiency
Hypokalemia
Routinely check levels, never give as IV

Question 9

Folic Acid

Answer 9

Nutritional supplement
Nutritional deficiency
Routinely check levels

Question 10

Erythropoietin

Answer 10

Procrit
Erythropoietic growth factor
Stimulate red blood cell formation
Need to have enough iron, folic acid and B12