Endo

Question 1

Hormone receptors types

Answer 1

•  Growth Factor- one cell membrane spanning domain in the monomer (Insulin, IGF-1, PRL, and GH)

•  G-protein coupled-serpentine receptor, seven cell membrane
spanning domains (NE, E, most hypothalamic and pituitary
hormones, PTH, and glucagon)

•  Guanylyl cyclase- one membrane spanning domain (Atrial
naturietic factor [ANF])

•  Nuclear hormone- binds to DNA, receptor usually resides in
nucleus (steroid, retinoic acid and thyroid hormones)