Sketchy Micro: Filovirus

Question 1

What kind of virus is Filovirus?

Answer 1

• Negative-sense ssRNA (like the nighttime scene with the moon in the background)
• Enveloped (like the ill-fitting, large soccer jersey worn by the fallen player)

Question 2

The nucleocapsid of Filovirus is ____________-shaped.

Answer 2

helical (like the helical orange rope that is tying the goal net on)

Question 3

Filovirus causes what two diseases?

Answer 3

• Ebola (like the e-gOal-a point being scored in the goal)

* Marburg (like the player Marburg)

Question 4

What are the symptoms of Ebola and Marburg?

Answer 4

• Fever (goalie sweating)
• Petechial rash (goalie with spotty sweat stains on his jersey)
• Hemorrhage (like the puddle of blood beneath the passed out player)
• End-organ failure (like the kidneys and liver spot on the fallen player’s uniform)
• Hypovolemic shock (like the lightning bolt on the fallen player’s uniform above his end-organ spots)

Question 5

What are the reservoirs for Filovirus?

Answer 5

Bats (like those hanging from the goal frame) and primates (like the ape first responders attending to the fallen player)

Question 6

In the U.S., most of the Ebola/Marburg patients are _____________.

Answer 6

healthcare works (like the red crosses on the apes’ backs)