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Endocrine > androgens > Flashcards

androgens Flashcards

1
Q

long term testosterone therapy

A

cypionate

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2
Q

short-term testosterone therapy

A

propionate

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3
Q

oral/buccal testosterone therapy

A

methyltestoserione

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4
Q

use of methyltestosterone

A

hypogonadism
delayed puberty
breast cancer

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5
Q

use of oxymetholone

A

anemia

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6
Q

general androgen uses

A

replacement therapy
stimulation of erythopoeisis
short stature
athletic performance

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7
Q

SE of androgens in women

A

virilization

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8
Q

SE of adrogens in men

A

impotence
gynecomastia
liver abnormalities
psychotic episodes

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9
Q

SE fo androgens in kids

A

epiphyseal closure

abnormal sexual maturation

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10
Q

antifungal antiandrogen

A

ketoconazole

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11
Q

diuretic antiandrogen

A

spirololactone

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12
Q

MOA of ketoconazole and spirololactone

A

competitive antagonists of cholerterol esterase

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13
Q

where spirolactone works

A

androgen-receptor complex and testis

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14
Q

blocks 5-alphareductase

A

finasteride

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15
Q

MOA of finasteride

A

testosterone conversion to dihydrotestosterone

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16
Q

supresses GnRH supression

A

cyproterone acetate

17
Q

competitive agonist of DHT-AR binding with progesterone like activity

A

cyproterone acetate

18
Q

pure competitive antiandrogen

A

flutamide

19
Q

blocks negative feedback loops

A

flutamide

20
Q

uses of antiandrogens

A 
prostatic hyperplasia and cancer
acne
male pattern baldness
virilization syndomres
precocious puberty
chemical castration
21
Q

antiandrogen for prostate cancer

A

leuprolide

Endocrine (13 decks)

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