Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MCD Y2: Microbiology > Microbiology 4: Skin infections > Flashcards

Microbiology 4: Skin infections Flashcards

1
Q

WHat % of GP consultations in the UK are skin-related?

A

15%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

In which climates are skin conditions most prevalent?

A

Hot and humid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which pathogen is responsible for tinea infections

A

Tricophytum rubrum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What sort of infection is caused by tricophytum rubrum?

A

Tinea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What sort of pathogen is trycophytum rubrum?

A

Fungus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Give 3 examples of tinea infections

A

Tinea capitis
Tinea ungulum
Tinea manu (“ringworm”)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Which pathogen is responsible for causing scabies?

A

Sarcoptes scabei

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Recall the pathophysiology of a scabies infection

A

Sarcoptes scabei burrows into the infected epidermis to cause a Type IV DTH reaction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Give 3 common sites for scabies burrows

A

Groin
Axilla
Anticubital fossae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Recall the main symptom of a scabies infection and how long the latent period is before symptoms are seen

A

Widespread erythrematous rash

4 week latent period

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What classification of bacterium is S aureus?

A

G+ coccus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Recall the 4 toxins produced by S aureus

A

PVL
Exfoliative toxin
TSS1
Enterotoxin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the result of PVL production by S aureus?

A

Causes necrotising infection

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the result of exfoliative toxin production by S aureus?

A

Blisters

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Recall 3 symptoms of S aureus infection?

A

Skin infection
Severe pneumonia
Sepsis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is impetigo?

A

An S aureus infection of the subcorneal layer of the epidermis

17
Q

Recall the appearance of imeptigo

A

Yellowish with golden crust, eroded base

18
Q

In what subset of the population is bullous impetigo most common?

A

Neonates

19
Q

What is ecythema?

A

Full thickness involvement of the epidermis in an S aureus infection

20
Q

What is the result of exfoliative-toxin productioon by S aureus?

A

Staphlococcal Scalded skin Syndrome

21
Q

Recall the pathophysiology of staphylococcal scalded skin syndrome

A

S aureus releases exfoliative toxin into the bloodstream at wound site
–> systemic infection –> widespread erythema

22
Q

Differentiate SSSS and toxic epidermal necrolitis

A

SSSS does not infect the mucous membranes but TEN does

23
Q

What sort of pathogen is treponema pallidum?

A

G- bacterium

24
Q

What is syphillis caused by?

A

Treponema pallidum

25
Q

Recall the duration of each of the phases of syphillis infection

A 
Primary = 3-8 weeks
Secondary = 6-12 weeks
Tertiary = years later
26
Q

Recall the main symptoms of the primary phase of syphillis

A

Chancre (painless ulcer) in genital/ oral area

27
Q

Recall the symptoms of secondary syphillis

A

Generalised rash, lymphadenopathy and flu-like illness

28
Q

Describe the rash of secondary syphillis

A

Maculopapular and erythrematous

29
Q

Which body systems are affected by tertiary syphillis?

A

Skin
CNS
PNS
CVS

30
Q

What is the first-line treatment for congenital syphillis?

A

Penicillin

31
Q

Recall which serotypes of HHV are known as EBV, VZV and CMV

A 
EBV = HHV4
VZV = HHV3
CMV = HHV5
32
Q

Recall which types of HSV cause oral and genital herpes

A 
Oral = type 1
Genital = type 2
33
Q

Which cells are infected in an HSV infection?

A

Neurons

34
Q

Which pathogen commonly infects at defective skin barriers due to eczema?

A

HSV –> eczema herpeticum

35
Q

What disease is produced by herpes spreading to the brain?

A

Herpes encephalitis

36
Q

Which serotype of HHV is associated with Kaposi’s sarcoma?

A

HHV8

37
Q

Where does VZV have latency?

A

Dorsal root ganglia

38
Q

Recall a virus that can cause non-cardiac chest pain

A

VZV when it is reactivated in shingles

39
Q

How does treatment of VZV differ in shingles that does/ does not affect CNV?

A

When CNV is infected you get face involvement so acyclovir is given IV rather than orally so as to avoid blindess

MCD Y2: Microbiology (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions