Pain + Thermo-sensation

Question 1

what is nociceptive?

Answer 1

pin prick sensation

Question 2

where is nociceptive cell bodies located?

Answer 2

dorsal roots of trigeminal ganglia

Question 3

what are the 2 types of fibres found?

Answer 3

Alpha delta and C fibers

Question 4

how many types of alpha delta fibres are there?

Answer 4

2

Question 5

what is type 1 alpha delta activated by?

Answer 5

heat

Question 6

what kind of receptors do type 1 alpha delta have?

Answer 6

high threshold mechanoreceptors –> slow sensation

Question 7

what do alpha delta type 2 fibres respond to?

Answer 7

noxious stimuli - harmful/unpleasant

Question 8

what is alpha delta type 2 fibres sensitive to?

Answer 8

capsaicin - sensation of burning

Question 9

what do all c fibres respond to?

Answer 9

all noxious stimuli

Question 10

what is the function of C-MH?

Answer 10

c fiber - detects mechanical stimuli by being activated by noxious heat
able to locate exact location of stimuli

Question 11

what is the function of C-M?

Answer 11

mechanical stimuli but insensitive to heat + capsalcin

Question 12

what is the function of C-H?

Answer 12

sensitive to capsalcin + mediates heat detection but does not contribute to location of stimuli

Question 13

what is the function of C-MH (silent)?

Answer 13

insensitive to heat or mechanical pain

sensntive to capsalcin + other analgesia

Question 14

what are the 2 terminals involved in signalling of noiceptors?

Answer 14

central and peripheral terminals

Question 15

what does the central terminal cause?

Answer 15

hyperalgesia

Question 16

what is the role of the central terminal?

Answer 16

large role in heat sensitivity

Question 17

what is the peripheral terminal responsible for?

Answer 17

environmental stimuli

large role in mechanical sensitivity