Environmental III

Question 1

cyanide attaches to and inactivates ____; principal toxicity is due to inactivation of ______

Answer 1

• cyanide attaches to and inactivates metalloenzymes; principal toxicity is due to inactivation of cytochrome c oxidase
• uncouples mitochondrial oxidative phosphorylation
  
  • inhibits cellular respiration, even in the presence of adequate O2 stores

Question 2

aflatoxin B is a carcinogen that can lead to ____

Answer 2

aflatoxin B is a carcinogen that can lead to hepatocellular cancer

Question 3

describe a contusion

Answer 3

• contusion
  
  • blunt force rupture blood vessels
    
    • subsequent hemorrhage
    • skin (or other tissue) remains intact

Question 4

describe features of a laceration

Answer 4

• laceration
  
  • tissue bridges
  • irregular edges

Question 5

describe the classification of cutaneous burns

Answer 5

Question 6

describe risk factors for heat stroke

Answer 6

• risk factors:
  
  • high ambient temp. and high humidity
  • young or elderly
  • alcoholism
  • medications
    
    • anticholinergics, antipsychotics
    • cardiovascular disease
    • dehydration

Question 7

describe the mechanisms of injury or death

Answer 7

Question 8

tissued composed of ____ are more sensitive to radiation than tissues with _____

Answer 8

tissued composed of rapidly dividing cells are more sensitive to radiation than tissues with slowly or non-dividing cells

Question 9

describe acute/early tissues responses to radiation vs. delayed/late

Answer 9

Question 10

describe hematopoietic syndrome

Answer 10

Question 11

describe gastrointestinal syndrome

Answer 11

Question 12

describe CNS/cardiovascular syndrome

Answer 12

Question 13

describe the effects of UV radiation

Answer 13