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122 E03 > T01 Intro to Infectious Diseases > Flashcards

T01 Intro to Infectious Diseases Flashcards

1
Q

Edward Jenner

A

cowpox virus, 1796

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2
Q

Louis Pasteur

A

germ theory of disease, LA vaccine for rabies 1865

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3
Q

Robert Koch

A

Koch Postulate

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4
Q

Koch Postulate (basically pasa pasa)

A

causal organism found in disease lesions; organism should be isolated in culture; secondary inoculation cause lesions; organism recoverable from experimental, 1882

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5
Q

Oswald Aery

A

DNA transmission of genetic traits (S.pneumo), 1944

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6
Q

Extracellular Infectious Pathogens

A

Mycoplasm, Bacteria, Fungi, Protozoa, Helminths

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7
Q

Mucosal Infectious Pathogens

A

Bacteria, Fungi, Protozoa, Helminths

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8
Q

Facultative intracellular Infectious Pathogens

A

Baceria, Fungi, Protozoa

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9
Q

Cutaneous Infectious Pathogens

A

Bacteria, Fungi

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10
Q

Example of Facultative Intracellular in Protozoa

A

Trypanosoma cruzi/Chagas Disease

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11
Q

Obligate Intracellular in Protozoa

A

Leishmania donovani/ Kala-azar

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12
Q

Which is not a mucosal pathogen Vibrio Cholera, Trichophyton spp, Giardia lambia, E. vernicularis

A

Trichophyton spp

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13
Q

Histoplasmosis is a disease caused by what kind of fungi

A

Facultative Intracellular fungi Histoplasma capsulatum

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14
Q

Chlamydia and Rickettsia

A

Obligate Intracellular

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15
Q

Kala-azar

A

Obligate Intracellular protozoa

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16
Q

What is seen in histologic sections of virus

A

Cytopathic changes or inclusions

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17
Q

Peptidoglycan composition

A

sugar, amino acid

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18
Q

FYBacBorreBru

A

Zoonotic bacterial infections

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19
Q

HBC

A

Contageous Childhood bacterial disease

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20
Q

Mycobacterial infections

A

Tuberculosis and leprosy

21
Q

Syphilis and bejel are

A

Human treponemal infections

22
Q

What do antifungals target in fungi

A

chitin walls, ergosterol cell membranes

23
Q

Thermal dimorphism

A

Room temp = Hyphae; Body temp = yeast

24
Q

Ascospores are sexual spores and more common

A

F, conidia (asexua) more common

25
Q

Binary fission

A

divison of CRM

26
Q

CRM sensitive to

A

antibiotics

27
Q

Mycoplasma cannot synthesize ATP

A

F, Chlamydia; Mycopasma lack cell wall

28
Q

arthropod vectors, mammalian hosts

A

Rickettsia

29
Q

Mycoplasma is strictly anaerobic since and has special characteristic for metabolizing galactose

A

F, aerobic siya and GLUCOSE

30
Q

single celled orgs that replicate in RBCs and hepatocytes; and in macrophages or Urogenital system/Intestine respectively

A

Plasmodium, Leishmania

31
Q

Scolex and NO digestive tract is is characteristic of Nematode

A

F, Cestode

32
Q

Syncytial tegument and sucker is characteristic of

A

Trematodes

33
Q

Ascaris and Strongyloides stercoralis have collagenous non-segmented tegument

A

T, since they are nematodes

34
Q

Treponema pallidum and Schistosoma can penetrate intact skin

A

T

35
Q

Phagocytic killing of alveolar macrophages can be evaded by

A

Mycobacterium tubercolosis

36
Q

IgA is Ig present in Interstinal tract

A

T

37
Q

Immune evasion

A

inaccessibility to host immune system; varying antigens

38
Q

what etermines whether foreign body will be pathogenic or not

A

Location

39
Q

Mechanisms of causing disease

A

infectious agents enter host; release endo/exotoxins, induction of host immune response

40
Q

Viral injury

A

tropism (HIV to CD4 T cells; Rhinovirus to ICAM-1)

41
Q

FLP Fungi, Legionellae, Pneumocystis

A

Silver stains

42
Q

Mucicarmine is used as stain for

A

Cryptococcus

43
Q

Organisms stained with Giemsa

A

CML- Campylobacteria, Leishmania, Malaria

44
Q

DNA probes can be used to diagnose

A

Virus, Bacteria, Protozoa

45
Q

Giemsa can be used to diagnose amoeba

A

F, PAS

46
Q

What can be used to diagnose ricketssia

A

Ab probes

47
Q

Rotavirus

A

childhood diarrhea

48
Q

Orchitis

A

Mumps

122 E03 (4 decks)

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