Chapter 20 Flashcards
Uncontrolled growth and proliferation of cells in a multicellular organisms ; bypass normal checkpoints in cell cycle;usually arise from one abnormal cell
Cancer
Can a single mutation in a cell cause cancer
No
Cancers arising from epithelial cells ( most common)
Carcinomas
Cancers arising from connective tissues or muscle cells
Sarcomas
Cancers that arise from cells in lymph nodes
Lymphomas
Cancers that arise from bone marrow or blood cells
Leukemia
When normal cells stop growing and proliferating when they are contacted on all sides with neighboring cells
Contact inhibition
When cancer cells lose contact inhibition and can pile on top of each other this group of cells are called
Foci
How does cancer utilize glucose different from how normal cells ?
They consume a lot more glucose and convert it into lactate even with presence of O2
Large consumption can aid in detection in body scans
How does cancer prevent apoptosis
Accumulated mutations which promotes genetic instability
Local Proliferation of cancer cells in initial stages form
Tumor or neoplasm
Localized neoplasm that can be removed easily
Benign
When cancer ( neoplastic) cells invade surrounding tissues
Malignant
When cells malignant tumors can break away from the tumor and move to other parts of the body and form new tumors it’s called ?
Metastasis
What involves cancer cells to successfully metastasize
Breaking free from previous tumor
Enter and exit blood stream
Colonize in different tissues
