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board review > microbiol toxins > Flashcards

microbiol toxins Flashcards

1
Q

ADP ribosylation

exotoxin A and diptheria toxin

inactivate EF-2 interfering with protein synthesis –> cell death

what bacteria?

A

Pseudomonas aeruginosa

theriaeCorynebacterium dip

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2
Q

overactivates adenylate cyclase (inc cAMP) by permanently activating Gs

increasing pumping of Cl- in Gut and H20 efflux

what bateria is responsible

which other bacteria has a similar mech

A

Vibrio cholerae

bordetella has a similiar mech

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3
Q

overactivates adenylate cyclase (inc cAMP) by

disabling Gi

impairing phagocytosis to permit survival of microbe.

what microbe?

A

bordetella pertussis

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4
Q

vibrio cholera and (ETEC) E coli - enterotoxigenic

use ADP ribosylating A-B toxin to cause?

A

watery diarrhea

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5
Q

bordetella pertussis

uses the ADP ribosylating A-B toxins to cause

A

whooping cough and lymphocytosis

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6
Q
A
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