board review Microbiology viruses Flashcards

1
Q

Q on boards

HSV1 causing herpetic keratitis

(fluorecein staining reveal dendritic ulcer (dendrite branches)

is the most common cause of CORNEAL blindess in US

true or false

A

true

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2
Q

Q on boards

what is the most common cause of death from encephalitis?

A

.HSV 1

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3
Q

pt presents with temporal lobe seizures symptoms

on the exam the pt smells burning rubber

diagnosis

A

HSV1 encephalitis

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4
Q

most common cause of blindness in US

A

diabetes

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5
Q

Q on boards

Tzanch test

will show what for HSV 1 -2

A

multinucleated epithelial giant cells w/ inclusion (cowdry type A )

(**eosinophilic nuclear inclusions**)

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6
Q

Q on boards

pt with Herpes zoster with trigeminal involvement (on the tip of the nose inidcating nasociliary branch infection) (hutchinsons sign)

what should you do?

A

consult ophthalmology

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7
Q

on the boards

  1. treatment of post herpetic neuralgia

2. capsaicin cream can be used to treat post herpetic neuralgia also

what is the moa?

  1. trick question they will put steriods as an answer choice.
A

1. gabapentin

or

TCA

2. depletes Substance P from the sensory nerve ending.

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8
Q

Q on board

1. HIV pt with Retinitis

(also can have Esophagitis, and pneumonia)

what is diagnosis and tx?

A

CMV

Ganciclovir

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9
Q

question on boards

giant cells w/ intranuclear inclusion bodies (owls eye)

(cells w/ basophilic inclusion bodies)

A

CMV

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10
Q

question on boards

you collect EBV and want to send the specimen for viral exam outside to lab.

how must you ship it to keep it viable?

A

frozen at -70 and shipped on dry ice

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11
Q

Q on boards

  1. EBV virus infects B cells by binding to what CD receptor?
  2. how can you tell if pt has an acute infection or previous infection
A
  1. CD21

2. acute: (heterophile) anti-EBV igM

previous IgG

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12
Q

on boards

pt is diagnosised with EPV

what is responsible for the enlarged lymphnodes and Splenomegaly

A

T cell proliferation

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