Conf 1 Rhumato D4 Flashcards

1
Q

Bilan bio avant donner MTX

A
Inhibiteur synthèse adn ( inhibe au niveau des tissus à renouvellement rapide )
NFS-P
foie : VHB VHC ALAT PAL albumine 
Poumon : radio tho
Beta HCG 
Creatinemie
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2
Q

Médoc CI avec le MTX

A

Bactrim

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3
Q

Qu’est ce que l’on associe au MTX Dans ttt PR?

A

Acide folique

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4
Q

CI au ttt par anti TNF alpha

A
  • atcd K évolutif
  • atcd patho demyelinisante : SEP / guillain barré
  • IC
  • infection
  • grossesse
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5
Q

Bilan pré TNF alpha

A
  • radio tho
  • quantiferon
  • ECBU
  • transaminases
  • sero VHB. VHC
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6
Q

EI colchicine

A

Diarrhée
Leuconeutropenies: aplasies
Toxidermie
Choc cardiogenique

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7
Q

Colchicine CI avec quel médocs?

A

Macrolides
Pristinamycine
( attention aux avk , fibrates et statines précautions emploi )

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8
Q

Principal EI allopurinol

A

Toxidermie

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