Lymphatic System and Immunity Flashcards

1
Q

in the lymphatic system, what are the vessels called?

A

lymphatic vessels

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2
Q

what is the fluid called that circulates the lymphatic vessels?

A

lymph

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3
Q

state some functions of the lymphatic system

A

drains excess interstitial fluid,
transports dietary lipids
carries out immune response

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4
Q

what are the two primary lymphatic organs?

A

red bone marrow and thymus

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5
Q

what are the secondary lymphatic organs?

A

lymph nodes, the spleen and lymphatic nodules

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6
Q

how many lymph nodes are found are the body?

A

around 600

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7
Q

where can lymph nodes often be found?

A

near mammary glands, the axilla and groin

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8
Q

what are the two types of immunity?

A
innate immuntiy (1st and 2nd line of defence)
adaptive (acquired) immunity
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9
Q

explain innate immunity

A

provided by the external physical and chemical barriers offered by the skin and mucous membranes, including: epidermis, cilia, saliva

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10
Q

name the innate immunity internal defences

A

antimicrobial substances (substances which discourage bacteria growth), natural killer cells and phagocytes, inflammation and fever

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11
Q

name the cells of the immune system

A

neutrophils, eosinophils, basophils, monocytes

t-cells, b-cells, natural killer cells, macrophages

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12
Q

explain what natural killer cells are and what they do?

A

5-10% of lymphocytes are NK cells.

They kill tumour cells and any cells that display abnormalities

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13
Q

explain what phagocytes are and what they do?

A

specialised cells that perform phagocytosis (cell-eating)

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14
Q

explain what macrophages and neutrophils are?

A

two types of phagocytes

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15
Q

explain phagocytosis

A

the pathogen interacts with the phagocyte receptors (binds with them)
the phagocyte engulfs the pathogen
this forms a phagosome
the phagosome forms with lysosome to make phagolysosome
enzymes digest the ingested pathogen
the phagocyte discards the waste materials

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16
Q

explain adaptive (acquired) immunity

A

offers a defence to specific to organism and foreign materials (‘non-self’)
provides a memory for most previously encountered antigens
involves lymphocytes called b-cells and t-cells

17
Q

what stops the lymph from going backwards in the lymphatic vessels?

A

valves

18
Q

what helps the movement of lymph in the lymphatic vessels?

A

smooth muscle contracts, skeletal muscles

19
Q

where are b-cells produced?

A

in the bone marrow

20
Q

where are t-cells matured?

A

thymus

21
Q

when do B-cells respond?

A

when pathogens are outside of the cell

22
Q

when do t-cells respond?

A

they respond in the cell-mediated response when the pathogens are inside of the cell