Pneumoconioses

Question 1

Occupations associated with asbestosis:

Answer 1

plumbing, shipbuilding, roofing

Question 2

Location of asbestosis:

Answer 2

lower lobes

Question 3

What is seen on sputum in asbestosis:

Answer 3

ferruginous bodies

Question 4

What is seen on CXR in asbestosis:

Answer 4

supradiaphragmatic calcified pleural plaques

Question 5

Risks seen with asbestosis:

Answer 5

increased risk of bronchogenic carcinoma > mesothelioma

increased risk of pleural effusion

Question 6

Occupations associated with Berylliosis:

Answer 6

beryllium exposure, aerospace work

Question 7

What is seen on CXR in Berylliosis:

Answer 7

non-caseating granulomas

Question 8

Risks associated with Berylliosis:

Answer 8

increased risk of cancer and cor pulmonale

Question 9

Occupation associated with coal worker’s pneumoconiosis:

Answer 9

coal miners

Question 10

What is seen in sputum in coal workers pneumoconiosis:

Answer 10

macrophages filled with carbon–“black lung dz”

Question 11

Location of coal workers pneumoconiosis:

Answer 11

Upper lobes

Question 12

Syndrome associated with coal worker pneumoconiosis:

Answer 12

Caplan syndrome: RA and pneumoconiosis with intrapulmonary nodules

Question 13

Occupation associate with silicosis:

Answer 13

sandblasting, foundries, mines

Question 14

Pathogenesis of silicosis:

Answer 14

Macrophages respond to silica –> produce fibrogenic factors –> fibrosis

Question 15

Location of silicosis:

Answer 15

upper lobes

Question 16

What is seen on CXR in silicosis:

Answer 16

eggshell calcification of hilar LNs

Question 17

Risks with silicosis:

Answer 17

silica disrupts phagolysosomes, impairs macrophages leading to and increased susceptibility to TB