6C - Regulation of blood glucose Flashcards
(44 cards)
Hyperglycaemia Definition
Where the level of sugar in your blood is too high
Hypoglycaemia Definition
A condition where the level of glucose in the blood drops below a healthy range
Glucagon Definition
A hormone formed in the pancreas which promotes the breakdown of glycogen to glucose in the liver
What is glucose?
Provides the body with energy for cellular respiration.
Glycogenesis Defintion
Glucose molecules joined to form glycogen
Glycogenolysis Definition
Glycogen is broken down into glucose
Normal blood glucose levels
4.0 mmol/L - 7.8 mmol/L
Maintaining Blood glucose levels
Maintained by the pancreas which produces hormones Insulin and glucagon
What does Islets of Langerhans do?
They are receptors in the pancreas and they detect a change in blood glucose levels.
What do beta cells do
Cause release of Insulin
What do alpha cells do?
Causes the release of glucagon
Once the glucose levels are detected, what do the hormones act on?
- Insulin causes excess glucose to be stored as glycogen.
- Glucagon converts glycogen into glucose
Stimulus response model for the increase in blood glucose levels
Stimulus- Blood glucose levels increases
Receptors - Islets of Langerhans (Beta cells release insulin)
Modulator- Pancreas
Effector - Skeletal muscles/fat cells, liver cells
Response- Increase uptake of glucose. Glucose is converted to glycagon/stored in liver
Stimulus response model for when blood glucose levels decrease
Stimulus- Blood glucose levels decrease
Receptors- Islets of Langerhans (alpha cells secrete glucagon)
Modulator- Pancreas
Effector- Liver cells
Response- Glycogen is released into bloodstream as glucose
How does glucagon differs from glycogen?
Glucagon- is a hormone that tells the body to raise blood sugar
Glycogen- Stored glucose used for energy
What does insulin do?
regulates the amount of glucose in the blood
If you ate at 9 and your blood sugar levels are up and then the insulin brings it down. why does the blood sugar levels rise again at 10am?
The rise was due to the body converting glycogen to glucose
state the type of molecule insulin represents.
A hormone
How does insulin cause a decrease in blood glucose concentration?
Insulin promotes the uptake of glucose into skeletal muscle and fat cells by increasing the amount of glucose transporters in their plasma membranes and increases the production of glycogen in the liver by liver cells.
What is the primary hormone responsible for lowering blood sugar levels?
Insulin
True or False: Glucagon raises blood sugar levels.
True
Fill in the blank: The pancreas produces insulin in response to _______.
high blood sugar levels
What organ is primarily responsible for regulating blood sugar levels?
Pancreas
What is the condition called when blood sugar levels are consistently high?
Hyperglycemia