Gout

Question 1

gout results from deposition of what in the synovium?

Answer 1

uric acid

Question 2

what indicates chronic deposition of urate?

Answer 2

tophi

Question 3

in gout what would you see under microscope?

Answer 3

negatively bifringent needle shaped crystals

Question 4

what is first line for acute gout?

Answer 4

NSAIDS

Question 5

what is second line in gout

Answer 5

colchicine

Question 6

side effect of colchicine?

Answer 6

D+V colosseum

Question 7

what kind of medication is allopurinol

Answer 7

xanthane oxidase inhibitor

Question 8

why is allopurinol not given in the acute setting?

Answer 8

it can exacerbate acute attacks

Question 9

what can be given if allergic to allopurinol?

Answer 9

febuxostat

Question 10

what is a uricosuric

Answer 10

drug that increases the excretion of uric acid in the urine

Question 11

examples of uricosurics?

Answer 11

• Sulfinpyrazone
• Probenicid
• Amplodipine
• Losartan
• Fenofibrate

Question 12

what are uricosurics used for in gout

Answer 12

preventative

Question 13

what kind of crystals do you get in psuedogout?

Answer 13

calcium pyrophosphate

Question 14

what condition is psuedogout associated with?

Answer 14

OA

Question 15

what is mono arthritis?

Answer 15

inflammation of one joint at a time

Question 16

what joints does pseudo gout affect?

Answer 16

knees, hips, shoulders

Question 17

which metabolic conditions is it associated with?

Answer 17

haemochromatosis
hyperparathyroidism
hypothyroidism

Question 18

pseudogout also known as?

Answer 18

chondrocalcinosis

Question 19

crystals in pseudogout?

Answer 19

positively bifringent rhomboid shaped

Question 20

treatment of pseudo gout?

Answer 20

there is no prophylactic treatment for psuedogout
NSAIDS
corticosteroids