ASD- 5A

Question 1

What are the two symptom categories for diagnosis of autism spectrum disorder?

Answer 1

• Deficits in social communication and interaction

- Restricted, repetitive behavior, interests, or activities

Question 2

Important criterion for diagnosing co-morbid intellectual disability and autism spectrum disorder

Answer 2

-social communication should be below that expected for general developmental level

Question 3

List the early signs of autism

Answer 3

• no big smiles or other warm expression by six months or thereafter
• no back and forth sharing of sounds, smiles, or other facial expressions
• no babbling by 12 months
• no words by 16 months
• no meaningful 2 word phrases by 24 months
• any signs of regression

Question 4

Epidemiology of ASD

Answer 4

• prevalence 14/1000
• M:F 4:1
• prevalence in siblings 4.5%
• onset in childhood

Question 5

Etiologies of autism

Answer 5

• Primary autism: 90-95% of cases
• Secondary autism: 5-10%, due to genetic mutations with autosomal dominant transmission
  
  • Fragile X (most common)
  • Tuberous sclerosis
  • Rhett syndrome (MeCP2 mutation- females only)

Question 6

What are the components of the medical assessment for Autism Spectrum Disorder

Answer 6

• hearing and vision test
• physical exam for dysmorphisms
• lead levels
• EEG: 25% of ASD develop seizure disorder
• FMR-1 DNA test for Fragile X syndrome

Question 7

The antipsychotics approved by the FDA for “irritability associated with autistic disorder”:

Answer 7

-Risperidone & Aripiprazole

Question 8

Behavioral treatment for Autism Spectrum Disorder

Answer 8

-Applied Behavior Analysis and Modification