Autoimmune liver disease Flashcards
1
Q
Primary biliary cholangitis
A
Granulomatous inflammation due to an auto-immune response
- Predominant in female
- IgM
- Related to an extra-hepatic duct obstruction
- Anti-mitochondrial auto antibodies present in serum
2
Q
Autoimmune hepatitis
A
- Mainly female
- IgG
3
Q
Primary sclerosis cholangitis
A
- Male predominant
- pANCA responsive
- extra-hepatic and intra-hepatic obstruction
- Chronic inflammation- fibrous obliteration of bile ducts
- Can lead to cirrhosis
