7.3: Skin disorders Flashcards
(21 cards)
What in the skin plays a role in cell signalling
Keratin
Keratinocytes in what skin layer lack nuclei or organelles
Stratum corneum
Where is melanin synthesised
In Melanocytes
Where does the vascular plexuses lie
In the dermis
Do not cross into epidermis
Characteristics of the reticular dermis
Superficial, composed of loose connective tissue
The skin has roles in what kind of immunity
Adaptive and innate
Where are T-cells resident
In the skin
Where are Langerhans cells resident
In the epidermis
What do keratinocytes synthesise
Antibiotics
3 functions of the skin
Thermoregulation
Immunity
Fluid balance
What nerve receptor senses vibration
Meissners corpuscle
What receptors sense pain and temp
Free nerve receptors
What receptors monitor skin stretch
Ruffini corpuscles
What receptors monitor light touch
Merkel cells
Function of desmosomes
Anchor keratins to the cell membrane
Function of adherens junctions
Bind intracytoplasmic actin
Function of gap junctions
Contain intracellular channels that directly connect cytoplasm of adjacent keratinocytes
Essential for cell synchronization, cell differentiation, cell growth and metabolic coordination
Function of connexons
Facilitate metabolic coordination between adjacent keratinocytes
What occurs in the catagen phase of the hair cycle
Hair disconnected from blood supply and becomes club hair
What happens in the Telogen phase of the hair cycle
Hair follicle is resting and hair shed.
Catagen cannot occur again until after anagen
What skin condition does staphylococcus aureus contribute to
Eczema
