Endocrinology Flashcards

1
Q

Prolactin secreted from where

A

Anterior pituitary

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2
Q

Excess prolactin men features

A

Loss of libido
Galactorrhoea
Impotence

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3
Q

Excess prolactin women

A

Amenorrhoea

Galactorrhoea

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4
Q

Causes of raised prolactin

A
Prolactinoma 
Pregnancy
Oestrogen
Drugs (metocloperamide)
Acromegaly 
PCOS
PRIMARY HYPOTHYROIDSIM
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5
Q

Hba1c target in T1DM

A

48

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6
Q

If patient symptomatic of t2dm, what glucose tests are diagnostic

A

Fasting > 7

Random > 11.1

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7
Q

Astmptommatic t2dm, what test and value is diagnostic

A

Hba1c > 48

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8
Q

What value of fasting glucose is impaired glucose tolerance

A

6.1-7

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9
Q

Drug causes of gynacomastia

5

A
Spiro 
Digoxin 
Cimetidine
Cannabis
Finasteride
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10
Q

Androgen high or low to cause gynaecomastia

A

Low

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11
Q

Causes of gynaecomastia

5

A
Testicular failure
Androgen failure (klinefelters)
Liver disease
Testicular cancer
Hyperthyroid
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12
Q

Best test to measure response of levothyroxine

A

TSH

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13
Q

When to add second drug in t2dm

A

When Hba1c hits 58

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14
Q

Target blood pressure in diabetics

A

140/80

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15
Q

Target bp on diabetics with end organ damage

A

130/80

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16
Q

Steroids linked to AVN

A

Remember

17
Q

Next line medications after metformin in order

A

Sulfonylurea
Gliptin
Pioglitazone
SGL 2 inhibitor

18
Q

Hashimotos tender or non tender goitre?

A

Non tender

19
Q

De quervains thyroiditis tender non tender?

A

Tender

20
Q

What to do with hydrocortisone and fludrocort doses when Ill

A

Double hydrocort

Keep fludrocort same

21
Q

Iron tablets reduce the effect of levothyroxine?

A

Yes

22
Q

Cushings disease caused by

A

Increased ACTH from ant pituitary

Ectopic ACTH lung cancer

23
Q

Drug cause of galactorrhoea

A

Metocloperamide
Domperidone
Phenothiazine (carbamazepine)

24
Q

Treatment of high prolactin

A

Bromocriptin

25
Q

Secondary hypothyroid is

A

Low TSH low T4

26
Q

Commonest cause of primary hypothyroidism

A

Hashimotos

27
Q

Hba1c > 48 and what = diabetes

A

Symptomatic patient

28
Q

Tsh/t4 in sick euthyroid

A

Low/normal

Low t4

29
Q

When is piaglitozone contraindicated

A

Heart failure as can cause fluid retention

30
Q

Parathyroid hormone raised/normal/low in primary hyperparathyroidism

A

Can be raised or normal

31
Q

First line aldosterone antagonist for primary hypoaldosteronism?

A

Spironolactone

32
Q

Causes of primary hypoaldosteronism

A

Conn’s (adrenal tumour)

Idiopathic

33
Q

First line investigation for primary hypoaldosteronism

A

Aldosterone/renin ratio

CT abdo

34
Q

What to do if not tolerating metformin side effects

A

Switch to modified release preparation in the evening

35
Q

Steroids cause which wbc to rise

A

Neutrophils