Eosinophilic Pustular Folliculitis

Question 1

Eosinophilic Pustular Folliculitis

Answer 1

repetitive eruption of pruritic follicular papules and pustules

Question 2

Epidemiology

Answer 2

very rare, cases in Japan. Average onset 30 years.

Question 3

Pathogenesis

Answer 3

unknown, may be related to mast cells

Question 4

Clinical signs

Answer 4

pruritic follicular pustules and papules, eruptive nature, erythematous patches and plaques with central clearing with annular lesions.

Question 5

Lesions last how many days

Answer 5

7-10 days, spontaneously resolve then recur in 4 weeks

Question 6

Locations

Answer 6

face, back, extensor arms

Question 7

Dermatopathology

Answer 7

spongiosis, eosinophils in follicular epithelium. Hallmark: infundibular eosinophilic pustules

Question 8

Location in infants

Answer 8

scalp

Question 9

Treatment

Answer 9

oral antihistamines for itch, topical steroids, calcineurin inhibitors. Indomethacin 50mg/day. UVB, Minocycline 100mg BID, Dapsone 100mg/day x 2 weeks