GI Secretion Flashcards

1
Q

what are the three salivary glands

A

parotid, submandibular, sublingual

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2
Q

how does saliva prevent tooth decay

A

carries IgA

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3
Q

what cells secrete digestive enzymes such as a-amylase

A

serous cell with zymogen granules

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4
Q

where do electrolytes move in salivon

A

sodium and Cl absorbed

K and HCO3- secreted

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5
Q

electrolyte modification primarily takes place in

A

striated ducts

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6
Q

a fast rate of secretion will have a _____ NaCl content

A

higher

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7
Q

what are the components of saliva

A

IgA, muramidase (lysozyme), lactoferrin (quenches iron), thiocyanate ions (destroys bacteria), EGF, NO leukocytes

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8
Q

difference in sympathetic and parasympathetic stimulation of saliva

A

sympathetic is B adrenergenic, short lived, and more viscous

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9
Q

what are the effects of mineralcorticoids on Na and K

A

increase na absorption, K secretion

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10
Q

what is the affect does ADH have on of Na reabsoption

A

increase

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11
Q

how does parasympathetic increase salivation

A

directly and by increases blood flow

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12
Q

pyloric glands contain what cells

A

G cells, secrete gastrin

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13
Q

oxyntic glands contain what cells

A

prietal cells (HCl), endrocrine cells, chief cells

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14
Q

surface mucous cells secrete

A

mucous and HCO3-

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15
Q

what do D cells produce

A

somatostatin

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16
Q

what stimulates gastrin secretion

A

gastrin, ACh, and histamine

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17
Q

what transporter produces HCl in parietal cells

A

H/K atpase, source is from H2Co3 produced by CA

18
Q

blood leaving the stomach is

A

alkaline

19
Q

what converts pepsinogen to pepsin

A

HCl

20
Q

Intrinsic factor is secreted from

A

parietal cells, necessary for B12 absoprtion at distal ileum

21
Q

what nuerotransmitters does the vagus nerve use to produce gastric secretion

A

Ach, histamine

22
Q

G cells are stimulated by

A

GRO

23
Q

parietal cells histamine receptors are blocked by

A

cimetidine and rantidine

24
Q

what does somatostatin do

A

decrease gastrin (acts in duodenum)

25
Q

what peptide from small intestine and endocrine cells inhibit parietal cells

A

gastric inhibitory peptide

26
Q

acid, FA, hyperosmolar chyme in duodenum stimulate

A

enterogastrones

27
Q

what enzyme breaks down basic AA

A

trypsin

28
Q

what enzyme breaks down aromatic AA

A

chymotrypsin

29
Q

where are pancreatic enzymes produced

A

acinar cells

30
Q

HCO3 secretion in pancrease is associated with ____ tide in plasma

A

acid

31
Q

what increases pancreatic secretion

A

ACh, secretin, and CCk

32
Q

secretion from Brunner’s gland (duodenum) is inhibited by

A

sympathetic tone

33
Q

secretion from Brunner’s gland (duodenum) consists of

A

mucous and HCO3-

34
Q

secretion from Brunner’s gland (duodenum) is stimualted by

A

irritant, vagus, secretin

35
Q

sucrase, maltase, isomaltase, lactase are produced by

A

enterocytes, crypts of lieberkuhn

36
Q

what are the other functions of the crypts of lieberkuhn

A

replenishing dead/shed epithelial lining, protect the epithelial cells from damage

37
Q

what is etiology of cholera toxin

A

increase cAMP, increase Cl and H2O

38
Q

what does VIP do

A

increase small intestine secretion

39
Q

what is the large intestine response to irritation

A

excessive water and HCO3 loss

40
Q

What is the most common cancer of the small intestine

A

Lymphoma, seen in the peyer’s patches within the lamina propria

41
Q

What are the most common tumors in the LI

A

Adenocarcinoma