Colorectal Cancer Flashcards
1
Q
Pathology
A
Adenocarcinoma of large bowel and rectum
Majority develop from benign polyps which gain mutations
2
Q
Mutations
A
APC or p53 genes
3
Q
Signs of right sided cancer
A
Unexplained anaemia Tiredness Change in bowel habit Weight loos Colicky abdominal pain Lump in abdomen
4
Q
Left sided and rectal cancer signs
A
Rectal bleeding
Feeling of incomplete emptying
Worsening constipation
5
Q
Investigations
A
Barium enema
Sigmoidoscopy
CT colonography
6
Q
Management
A
Surgical
7
Q
Ceacal, ascending, proximal or transverse cancer sugergy
A
Right hemicholectomy
8
Q
Distal transverse or descending colon cancer management
A
Left hemicholectomy
9
Q
Sigmoid colon cancer surgery
A
Sigmoid cholectomy
10
Q
Low sigmoid, high rectum cancer surgery
A
Anterior resection
11
Q
Rectal cancer surgery
A
Trans anal endoscopic microsurgery, abdominal perineal resection
12
Q
Post-op
A
Chemo reduces local occurrence
Offered to Dukes C and above
