Blood flow Flashcards
flow rule
flow= pressure/resistance
Factors affecting resistance to flow
-Vessel radius 4th power effect Increase radius → decrease resistance -Vessel length Increase length → increase resistance -Fluid viscosity Increase viscosity → increase resistance
Equation
Blood flow= blood pressure X vessel radius^4 / vessel length X blood viscosity
flow=
cardiac output
pressure=
mean arterial pressure (MAP)
Resistance=
total peripheral resistance (TPR)
equation for CO
MAP/TPR
arterioles
- Small arteries that can change radius
- Most regulation of blood flow
- Greatest resistance
arteriole regulation
Vasodilation: increase radius
→ decrease resistance
Vasoconstriction: decrease radius
→ increase resistance
Control of arteriole regulation
Sympathetic nervous system
Endocrine system
sympathetic (what it innervates, action, results)
-Innervates smooth muscle of arterioles
-Action: vasoconstriction (most organ arterioles)
-Results:
Increase TPR
Increase MAP
Endocrine system
Epinephrine
Adh
Angiotensin II
Epinephrine (actions, results)
- Actions
- Vasodilation in skeletal and cardiac muscles
- Vasoconstriction in most vascular beds
- Results
- Increase blood flow to cardiac and skeletal muscle capillaries
- Decreased TPR → decrease BP
- Decreased blood flow to other areas
- Increase TPR → maintain BP
ADH (actions, results)
Actions: increases H2O reabsorption by kidneys, vasoconstriction
Results
- Increase TPR
- Increase MAP
Angiotensin (how its made, actions, results)
- Angiotensinogen → angiotensin I → angiotensin II
- Actions: vasoconstriction
- Results:
- Increase TPR
- Increase MAP