Acylation - nucleophiles Flashcards
1
Q
List the order of nucleophiles used in acylation from most reactive to least
A
Primary amine > ammonia > alcohol > water
2
Q
What product is made if the nucleophile is ammonia?
A
Amide
3
Q
What product is made if the nucleophile is a primary amine?
A
N-substituted amide
4
Q
What product is made if the nucleophile is an alcohol?
A
Ester
5
Q
What product is made if the nucleophile is water?
A
Carboxylic acid
